CAKUT, UTI and bladder disorders

Silvio Maringhini

Board Members
Giovanni Montini
Velibor Tasic
Fatos Yalcinkaya
Julia Hoefele

Liaison ESPN Registry: Marjolein Bonthuis
Liaison Council: Max Liebau



CME Activity: 
During in ESPN Porto 2014, CAKUT Master class. 4
During the ESPN in Brussels 04/09/2015 a Symposium was dedicated to research related to CAKUT
During  the ESPU Harrogate 24/06/2016 a Joint symposium of ESPU and ESPN CAKUT

Registry Activities: 
CAKUT Registry and Biobank (EURECa registry S. Weber, F. Yalcinkaya): under construction

ESPN/ERA-EDTA Registry data analysis on long-term outcome in Prune Belly syndrome: publication under review (Outcomes of renal replacement therapy in boys with prune belly syndrome: findings from the ESPN/ERA-EDTA registry)

Link with ESPN/ERA-EDTA Registry: Substudy of Progression of Renal Insufficiency in Patients with Congenital Malformations oft he Kidney and Urinary Tract (K. van Stralen)

Link with ESPN WG Inherited Disorders: (Chair M. Konrad)

Clinical studies: 
Link to the PREDICT-Trial (Initiators G. Montini, F. Schaefer)

Survey on management in renal dysplasia (G. Montini) : publication under review ( based on the questionnaire from the ESPN-WG CAKUT/UTI/Bladder WG)

Scientific studies: 
Gene Identification Studies in CAKUT (following set-up of the Registry)
Renal tract malformations: from human genomics to novel therapies” Adrian Woolf (under construction ).

Website Educational Material/Experts to be asked: 
UTI (G. Montini, F. Yalcinkaya), Bladder Dysfunction (A. Raes, A. Peco-Antic), CAKUT Genetics (S. Weber), Antenatal Management of CAKUT (K. Ismaili)

ESPN Working Group CAKUT Introduction

Minutes ESPN Working Group CAKUT

Management of Antenatal Hydronephrosis

Antenatal Assessment of Kidney Morphology and Function

Surgery in CAKUT

You can reach CME credit ESPN WG presentations from ESPN members area!

CAKUT,UTI and bladder disorders Working Group report September,2014 

Survey on renal dysplasia


Publications of interest:
Functional Models for Congenital Anomalies of the Kidney and Urinary Tract

Escherichia coli virulence patterns may help to predict vesicoureteral reflux in paediatric urinary tract infections

Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling

Timing and Outcome of Renal Replacement Therapy in Patients with Congenital Malformations of the Kidney and Urinary Tract Clin J Am Soc Nephrol 2013.

Pathogens causing urinary tract infections in children: a European overview by the Escape study. European journal of pediatrics 2015

Annual Reports:
CAKUT/UTI/Bladder Dysfunction Working Group Report , September2015

CAKUT/UTI/Bladder Dysfunction Working Group Report , August 2017

CAKUT/UTI/Bladder Dysfunction Working Group Report, August 2018


  •  The aim of the Society is to promote research knowledge of paediatric nephrology through teaching, scientific meetings and other methods, for the benefit of children with renal disease.

  •  World Kidney Day activities in ESPN Centres

  • ESPN Research Grant 2014 ; the call is closed & the results were announced at ESPN General Assembly Meeting in Porto.

  • If you wish to join the PEDNEPH forum then e mail your details to

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